5月25日讯/生物谷BIOON/通过回顾性研究发现,糖化血红蛋白测试常用于糖尿病的诊断和管理 ,可以有效地检测住院患者隐藏的一些疾病。
高血糖症是一种常见的与生理压力,疾病和药物,包括类固醇和血管加压药等相关的疾病。特罗加州大学和俄亥俄州大学的研究人员回顾了348名高血糖住院病人的医疗记录。这些患者中,有50人不知道自己的糖尿病史,他们中的31人通过糖化血红蛋白测试,测出平均血糖水平超出过去的8 - 12周的血糖水平。
在这些测试中,77%的患者结果符合糖尿病(58%)诊断结果或前驱糖尿病(19%)。最终,超过一半(55%)以前没有糖尿病史的患者接受了包括糖尿病的出院诊断。
“在医院里,当我们治疗其它疾病如败血症或心脏病时常常会发现患者还伴有高血糖。本研究发现,以前没有任何已知糖尿病史的患者通过糖化血红蛋白水平测定他们在出院时诊断为糖尿病的机率比入院时高出五倍。”Shubrook博士说。
Shubrook博士补充说,“这表明我们错过了检测糖尿病的机会,一开始就治疗这些病人可以减少他们的长期护理和疾病负担的成本。早期检测后应用整骨疗法可以得到更好的结果, 当高血糖被检测出用来区分瞬时高血糖症和慢性疾病时医院检测糖化血红蛋白是比较容易的。”
根据美国糖尿病协会称,大约五分之一的医疗费用花在糖尿病护理上,这是与住院治疗相关的最大比例花费。先前的研究发现,患者接受糖尿病诊断和接受住院治疗后会有一个较低的全因30天再入院率。(生物谷)
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A retrospective review of medical records found the HbA1C test, commonly used to diagnose and manage diabetes, can effectively detect hidden disease among hospital patients with hyperglycemia, commonly known as high blood sugar.
Hyperglycemia is a frequent finding that can be related to physiologic stress, illness and medications, including steroids and vasopressors. Researchers from Touro University California and Ohio University Heritage College of Osteopathic Medicine reviewed the medical records of 348 patients with hyperglycemia inpatients discovered at admission in a rural community teaching hospital in the Midwest. Of those patients, 50 had no known history of diabetes and 31 of them were given an HbA1C test, which measures the average blood glucose level over the previous eight to 12 weeks. Among those tested, 77 percent had results consistent with diagnoses of diabetes (58 percent) or prediabetes (19 percent). Ultimately, more than half (55 percent) of patients with no previous history of diabetes received a discharge diagnosis that included diabetes.
"In the hospital, we often find hyperglycemia when we e treating other illnesses, like sepsis or a heart attack. This study found that patients with no known history of diabetes whose HbA1C level was measured were five times more likely to leave the hospital with a diagnosis of new-onset diabetes," said Dr. Shubrook.