PINK1基因,PINK1 gene
1)PINK1 genePINK1基因
1.-2922(C)2-3, IVS6+18insG) of Nurrrl gene and Parkinson s disease (PD) in a Han population from Sichuan province; to find whether there were any big homozygous deletions or point mutations in thePINK1 gene in early-onset PD and two autosomal recessive Parkinson s disease families.目的：了解Nurr1基因多态性与四川地区散发性帕金森病之间的相关性；了解四川地区2个早发性帕金森病家系PINK1基因的缺失和突变情况；了解四川地区散发早发性帕金森病患者PINK1基因的缺失突变和点突变的情况。
2.To detect the mutation ofPINK1 gene in Chinese patients with early onset Parkinsonism (EOP) by using DHPLC.目的建立应用DHPLC技术检测PINK1基因突变的技术平台，对EOP患者进行PINK1基因突变筛查。
3.To investigate thePINK1 gene mutation between the EOP and LOP.本研究应用PCR、限制性片断长度多态性(restriction fragment length polymorphisms，RFLPs)、DNA测序技术检测parkin和PINK1基因外显子的缺失、点突变及多态性与帕金森病的关系，并结合对临床症状的分析，探讨基因缺失或突变是否能影响了PD患者临床症状包括非运动并发症的产生和进展，是否能作为帕金森病早期诊断的指标。
英文短句/例句
1.Mutation Analysis of PINK1 Gene by Using Denaturing High Performance Liquid Chromatography (DHPLC);应用DHPLC技术检测PINK1基因突变
2.The Studies of Mutations and Polymorphism on PINK1 Gene of Patients with Parkinson Disease in Guangxi广西地区帕金森病PINK1基因突变与多态性的研究
3.Detection of the Mutations of PINK1 Gene Using Real-time PCR and Direct Sequencing;应用实时荧光定量PCR技术结合DNA直接测序技术检测PINK1基因突变
4.Detection the Role of PINK1 Mutation and Oxidative Stress, Mitochondrial Dysfunction in the Pathogenesis of Parkinson Disease;PINK1基因突变与氧化应激、线粒体功能障碍在帕金森病发病机制中的作用研究
5.The Study of Parkin and Pink1 Gene in Patients with Parkinson s Disease;帕金森病致病基因parkin和PINK1的相关研究
6.Screening and Confirmation of Proteins Interacting with PINK1PINK1蛋白相互作用蛋白的筛选与鉴定
7.extinguisher loci消失基因座，绝灭基因座
8.Of, relating to, produced by, or being genes or a gene.基因的基因的，与基因有关的，基因产生的
9.Genes are described as DOMINANT or RECESSIVE.基因分为显性基因和隐性基因。
10.hypomorphic allele次等位因素对偶基因
11.Studies on Polymorphism of Prolactin Receptor Gene and Follicle-Stimulating Hormone Beta Subunit Gene in Swine;猪PRLR基因和FSHβ亚基基因多态性研究
12.Research on Hte Microarray Based Gene Mining Algorithm;基于基因表达谱的基因挖掘算法研究
13.Human Genome Project,Post-genome Research and Gene Medicine --New Century of Diagnosis,Pharmaceutics and Therapy with Gene Technique;人类基因组计划、后基因组研究与基因医学——基因诊断、基因制药与基因治疗的新世纪
14.Genetic material produced by gene-splicing.重组基因材料基因分割而产生的基因材料
15.Gene distribution was out of balance. Dominant genes were more than recessive ones.基因的分布是不对称的,显性基因多于隐性基因。
16.Association of apoE Gene, A2M Gene and ACE Gene Polymorphism with Alzheimer s Disease;apoE基因、A2M基因、ACE基因与汉人Alzheimer病的相关性研究
17.Study on Inheritance of the Quality Transgenes Over-expressed in Transgenic Wheat;转基因小麦外源基因品质基因表达的遗传研究
18.Legal Research on Gene Science and Technology--Does Gene Belong to Invention or Discovery;基因科技的法律问题研究——“发明”基因?“发现”基因?
相关短句/例句
PINK1PINK1基因
1.Detection of the Mutations ofPINK1 Gene Using Real-time PCR and Direct Sequencing;应用实时荧光定量PCR技术结合DNA直接测序技术检测PINK1基因突变
2.Detection the Role ofPINK1 Mutation and Oxidative Stress, Mitochondrial Dysfunction in the Pathogenesis of Parkinson Disease;PINK1基因突变与氧化应激、线粒体功能障碍在帕金森病发病机制中的作用研究
3.Objective: To study deletion mutations、point mutations and polymorphism ofPINK1 gene exons 1 to 8 in the GuangXi patients with Parkinson disease.方法:采用聚合酶链反应(polymerase chain reaction, PCR)扩增50例帕金森病组(其中早发性帕金森病28例、晚发性帕金森病22例)和55例相匹配的对照组(其中青年对照组17例、老年对照组38例)的PINK1基因1-8号外显子;用琼脂糖凝胶电泳(agarose gel electrophoresis,AGE)检测PCR产物是否为特异性扩增和PINK1基因1-8号外显子的大片段缺失突变;单链构象多态性分析(single strand conformation polymer phi- sm,SSCP)检测PINK1基因1-8号外显子的点突变,并对SSCP出现异常泳带的相应片断进行DNA直接测序,如果发现多态性位点,采用斑点杂交法进行检测进一步明确其基因型,并计算多态性位点的基因型频率和等位基因频率,所有实验结果采用卡方检验进行统计分析。
3)gene[英][d?i:n][美][d?in]基因
1.Study of the Preparation and the Characteristics of pRc/CMV-BChE Gene-chitosan nanoparticles ①;丁酰胆碱酯酶基因-壳聚糖纳米粒初步研究
2.Correlation between traditional Chinese medicine syndromes in primary immunoglobulin A nephropathy and A267G in 5"-untranslated region within exonal of megsingene;Megsin基因E1-5’UTR区A267G与免疫球蛋白A型肾病阴虚证的相关性
3.Study ongene chip of leiomyoma of uterus;子宫肌瘤基因芯片的研究
4)Genes基因
1.Study on Apoptosis of Human Leukemia Cells and Its RelatedGenes Regulation Induced by ~(235) U;浓缩铀诱发细胞凋亡的形态及基因调控
2.Screening of lymphatic metastasis-associated genes in esophageal squamous cell carcinoma;食管癌淋巴结转移相关基因筛选的研究
3.Study on the Genotyping of Aminoglycoside Modifying EnzymesGenes from Pan-drug Resistant Acinetobacter Baumannii.;泛耐药鲍曼不动杆菌氨基糖苷类修饰酶基因研究
5)Polymorphism[英][,p?li"m?:fiz?m][美][,pɑl?"m?rf?zm?]基因
1.The Study on Apolipoprotein E GenePolymorphism Characteristics of Cerebral Infarction and Intracerebral Hemorrhage;脑梗死与脑出血apoE-基因多态性特点研究
2.The Relations of GenePolymorphisms of eNOS and FⅦ with Coronary Heart Disease in Henan Han Population;河南汉族人群一氧化氮合酶和凝血因子Ⅶ基因多态性与冠心病相关性分析
3.Methods:Polymorphism of the 677th site C/T of MTHFR gene and the 66th site A/G of MTRR gene were detected by polymerase chain reaction-restrction fragment length polymorphism in disease group(n=64) and normal controls(n=104).目的:研究同型半胱氨酸相关酶中亚甲基四氢叶酸还原酶(MTHFR)及蛋氨酸合成酶还原酶(MTRR)基因的多态性与先天神经管缺陷的关系。
6)AS geneAS基因
延伸阅读
Cationic Pink FG分子式：C22H26Cl2N2分子量：398.35CAS号：3648-36-0性质：暗红色均匀粉状物。配伍值4。属半菁阳离子染料。溶于水呈鲜明桃红色，在硫酸中呈黄色，稀释后转红光橙色。制备方法：以N-甲基苯胺，环氧乙烷，三氯氧磷，二甲基甲酰胺和1,3,3-三甲基-2-亚甲基吲哚啉为基本原料。先由N-甲基苯胺用环氧乙烷进行羟乙基化，再用三氯氧磷进行氯化，用二甲基甲酰胺醛化，而后与1,3,3-三甲基-2-亚甲基吲哚啉缩合，最后过滤、干燥即得成品。原料消耗(kg/t)磷酸224 亚硫酸氢钠 580乙醇440 锌粉9氯磺酸 3560 硫酸360苯 750 甲乙酮 152甲醇930 氨水（25%） 680氢氧化钠（100%）430 N-甲基苯胺 178苯胺260 二甲基甲酰胺（DMF） 190盐酸（31%）1200 三氯氧磷550亚硝酸钠190环氧乙烷80用途：用于腈纶及其混纺织物的染色和印花。还可用于乙酸纤维和聚氯乙烯纤维的染色。
